- Generic Name: sertraline
- Dosage Forms: oral solution, concentrate
- Other Brand Names: Zoloft
What is Sertraline Oral Concentrate?
Management of major depressive disorder.
Efficacy in hospital settings not established.
APA states that effectiveness of antidepressants is generally comparable between and within classes of medications, including SSRIs, SNRIs, TCAs, MAOIs, and other antidepressants (e.g., bupropion, mirtazapine, trazodone). Choose antidepressant based mainly on patient preference; nature of prior response to medication; safety, tolerability, and anticipated adverse effects; concurrent psychiatric and medical conditions; and specific properties of the medication (e.g., half-life, actions on CYP450 enzymes, other drug interactions). For most patients, an SSRI, SNRI, mirtazapine, or bupropion is considered optimal. Consult APA’s Practice Guidelines for the Treatment of Patients with Major Depressive Disorder for additional information.
Obsessive-Compulsive Disorder (OCD)
Management of OCD; reduces but does not completely eliminate obsessions and compulsions.
Panic Disorder
Management of panic disorder with or without agoraphobia.
Posttraumatic Stress Disorder (PTSD)
Management of PTSD; more effective in women than in men.
Not effective for combat- or war-related PTSD.
Premenstrual Dysphoric Disorder (PMDD)
Management of PMDD; improves symptoms (e.g., depressed mood, premenstrual anger/irritability) and functional impairment (e.g., difficulty in concentrating, lethargy) associated with this disorder.
Efficacy when used in conjunction with oral contraceptives for the treatment of PMDD is unknown.
Social Phobia
Management of social phobia (social anxiety disorder).
Premature Ejaculation
Has been used in the management of premature ejaculation.
Vascular Headaches
Has been used in the management of vascular headaches with equivocal efficacy.