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Seconal and Porphyria

Result of checking the interaction of drug Seconal and disease Porphyria for safety when used together.

Check result:

Seconal <> Porphyria

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of barbiturates is contraindicated in patients with a history of porphyria. Barbiturates may exacerbate acute intermittent porphyria or porphyria variegata by inducing the enzymes responsible for porphyrin synthesis.

References:

American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association; (1994):
"Product Information. Nembutal Sodium (pentobarbital)" Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Butisol Sodium (butabarbital)" Wallace Laboratories, Cranbury, NJ.
"Product Information. Seconal Sodium (secobarbital)" Lilly, Eli and Company, Indianapolis, IN.
Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, eds. "Harrison's Principles of Internal Medicine. 14th ed." New York, NY: McGraw-Hill Health Professionals Division (1998):
"Product Information. Mebaral (mephobarbital)" Sanofi Winthrop Pharmaceuticals, New York, NY.
"Product Information. Amytal Sodium (amobarbital)" Lilly, Eli and Company, Indianapolis, IN.
"Product Information. Phenobarbital (phenobarbital)." Lilly, Eli and Company, Indianapolis, IN.

Seconal

Generic Name: secobarbital

Brand Name: Seconal, Seconal Sodium

Synonyms: n.a.

What is Seconal?