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Sandostatin LAR and Thyroid dysfunction

Result of checking the interaction of drug Sandostatin LAR and disease Thyroid dysfunction for safety when used together.

Check result:
Sandostatin LAR <> Thyroid dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Rarely, hypothyroidism requiring thyroid hormone replacement may occur during chronic therapy. More commonly, a statistically significant, but usually clinically insignificant, increase in TSH may be observed, possibly caused by slight inhibition of peripheral deiodination of thyroxin. Therapy with octreotide should be administered cautiously to patients with uncontrolled thyroid disorders. Clinical monitoring of thyroid function is recommended.

References:
  • "Product Information. Sandostatin (octreotide)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
  • Christensen SE, Weeke J, Kaal A, Harris AG, Orskov H "SMS 201-995 and thyroid function in acromegaly: acute, intermediate and long-term effects." Horm Metab Res 24 (1992): 237-9
Sandostatin LAR

Generic Name: octreotide

Brand Name: Sandostatin, Sandostatin LAR Depot

Synonyms: Octreotide (injection), Octreotide

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