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Rybix ODT and Drug dependence

Result of checking the interaction of drug Rybix ODT and disease Drug dependence for safety when used together.

Check result:
Rybix ODT <> Drug dependence
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Tramadol has the potential to cause dependence and abuse. Tolerance as well as physical and psychological dependence can develop after prolonged use. Abrupt cessation, reduction in dosage, or administration of an opiate antagonist such as naloxone may precipitate withdrawal symptoms. Tramadol may also reinstate physical dependence in patients previously addicted to or chronically using opioids. Therapy with tramadol is not recommended in patients with a tendency to drug abuse, a history of drug dependence (including alcoholism), or chronic use of opioids. After prolonged use or if dependency is suspected, withdrawal of tramadol therapy should be undertaken gradually using a dosage-tapering schedule.

References:
  • Brinker A, Bonnel RA, Beitz J "Abuse, dependence, or withdrawal associated with tramadol." Am J Psychiatry 159 (2002): 881; discussion 881-2
  • "Product Information. Ultram (tramadol)." McNeil Pharmaceutical, Raritan, NJ.
Rybix ODT

Generic Name: tramadol

Brand Name: ConZip, Ultram, Ultram ER, Rybix ODT, Ryzolt

Synonyms: Rybix ODT (Oral)

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