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Asendin and Tardive dyskinesia

Generic Name: amoxapine
Dosage Forms: n.a.
Other Brand Names: Asendin

Result of checking the interaction of drug Asendin and disease Tardive dyskinesia for safety when used together.

Check result:

Asendin <> Tardive dyskinesia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Although not a neuroleptic agent, amoxapine has substantive neuroleptic activity due to its postsynaptic dopamine-blocking effects and may precipitate or aggravate symptoms of tardive dyskinesia (TD) following chronic use. Neuroleptic-induced TD may or may not be reversible depending, at least partially, on the duration and total cumulative dose of neuroleptic therapy administered. The use of amoxapine should preferably be avoided in patients with TD. If amoxapine is given to these patients and worsening of TD occurs, prompt withdrawal of therapy will provide better chances of improving the condition.

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