Rucaparib and MDS/AML
Result of checking the interaction of drug Rucaparib and disease MDS/AML for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Cases of myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML) have been reported with the use of rucaparib. It is recommended to monitor complete blood count at baseline and monthly thereafter, and as clinically appropriate. Do not start rucaparib until patients have recovered from hematological toxicity caused by previous chemotherapy. It might be necessary to interrupt therapy with rucaparib until blood counts have recovered. If MDS/AML is confirmed, rucaparib should be discontinued.