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Acetaminophen, diphenhydramine, and phenylephrine and Asthma/COPD

Result of checking the interaction of drug Acetaminophen, diphenhydramine, and phenylephrine and disease Asthma/COPD for safety when used together.

Check result:

Acetaminophen, diphenhydramine, and phenylephrine <> Asthma/COPD

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

It has been suggested that the anticholinergic effect of antihistamines may reduce the volume and cause thickening of bronchial secretions, resulting in obstruction of respiratory tract. Some manufacturers and clinicians recommend that therapy with antihistamines be administered cautiously in patients with asthma or chronic obstructive pulmonary disease.

References:

"Product Information. Temaril (trimeprazine)" Allergan Inc, Irvine, CA.
"Product Information. Tavist (clemastine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
"Product Information. Periactin (cyproheptadine)." Merck & Co, Inc, West Point, PA.
Maddox DE, Reed CE "Clinical pharmacodynamics of antihistamines." Ann Allergy 59 (1987): 43-8
"Product Information. Semprex-D (acrivastine-pseudoephedrine)." Endo Laboratories LLC, Chadds Ford, PA.
"Product Information. Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO.
"Product Information. Phenergan (promethazine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
"Product Information. Tacaryl (methdilazine)." Westwood Squibb Pharmaceutical Corporation, Buffalo, NY.
"Product Information. Dimetane (brompheniramine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
"Product Information. Chlortrimeton (chlorpheniramine)." Schering-Plough, Liberty Corner, NJ.
"Product Information. Optimine (azatadine)." Schering Laboratories, Kenilworth, NJ.
"Product Information. Antivert (meclizine)." Roerig Division, New York, NY.
"Product Information. Drixoral (dextromethorphan)." Schering-Plough, Liberty Corner, NJ.
"Product Information. Benadryl (diphenhydramine)." Parke-Davis, Morris Plains, NJ.
"Product Information. Marezine (cyclizine)." Glaxo Wellcome, Research Triangle Park, NC.
"Product Information. Dramamine (dimenhydrinate)" Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Vistaril (hydroxyzine)." Pfizer US Pharmaceuticals, New York, NY.

Acetaminophen, diphenhydramine, and phenylephrine

Generic Name: acetaminophen / diphenhydramine / phenylephrine

Brand Name: Benadryl Allergy & Sinus Headache, Delsym Cough Plus Cold Night Time, Mucinex Fast-Max Night Time Cold and Flu, Robitussin Nighttime Multi-Symptom Cold, Sudafed PE Severe Cold, Theraflu Severe Cold & Cough Nighttime, Theraflu Warming Flu & Sore Throat, Theraflu Warming Sinus & Cold, Theraflu Warming Severe Cold Nighttime, Benadryl Allergy & Cold, Sudafed PE Nighttime Cold, Tylenol Allergy Multi-Symptom Nighttime, Theraflu Nighttime Severe Cough & Cold, Children's Delsym Cough Plus Cold Night Time, Children's Mucinex Night Multi-Symp Cold, Children's Dimetapp Multi-Symptom Cold & Flu, Theraflu ExpressMax Nighttime Severe C&C, Theraflu PowerPods Nighttime Severe Cold, Benadryl Allergy/Cold, Tylenol Allergy Multi-Symptom, Theraflu Warming Relief Nighttime Severe Cold

Synonyms: n.a.

What is Acetaminophen, diphenhydramine, and phenylephrine?