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Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine and PKU

Result of checking the interaction of drug Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine and disease PKU for safety when used together.

Check result:
Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine <> PKU
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Several oral acetaminophen and acetaminophen-combination products, particularly flavored chewable tablets, contain the artificial sweetener, aspartame (NutraSweet). Aspartame is converted to phenylalanine in the gastrointestinal tract following ingestion. Chewable and effervescent formulations of acetaminophen products may also contain phenylalanine. The aspartame/phenylalanine content should be considered when these products are used in patients who must restrict their intake of phenylalanine (i.e. phenylketonurics).

References:
  • "Product Information. Tylenol (acetaminophen)." McNeil Pharmaceutical, Raritan, NJ.
Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine

Generic Name: acetaminophen / dextromethorphan / pseudoephedrine / pyrilamine

Brand Name: Robitussin Night Relief

Synonyms: n.a.

Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine <> PKU
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Chewable products frequently may contain aspartame, which is metabolized in the gastrointestinal tract to phenylalanine. Sudafed (brand of pseudoephedrine) chewable 15 mg tablets provide the equivalent of 0.78 mg of phenylalanine per each tablet. The aspartame/phenylalanine content should be considered when this and similar products are used in patients who must restrict their intake of phenylalanine (i.e. phenylketonurics).

References:
  • "Product Information. Sudafed (pseudoephedrine)." Glaxo Wellcome, Research Triangle Park, NC.
Acetaminophen, dextromethorphan, pseudoephedrine, and pyrilamine

Generic Name: acetaminophen / dextromethorphan / pseudoephedrine / pyrilamine

Brand Name: Robitussin Night Relief

Synonyms: n.a.