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Reserpine, hydralazine, and hydrochlorothiazide and PUD/ulcerative colitis

Result of checking the interaction of drug Reserpine, hydralazine, and hydrochlorothiazide and disease PUD/ulcerative colitis for safety when used together.

Check result:
Reserpine, hydralazine, and hydrochlorothiazide <> PUD/ulcerative colitis
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of rauwolfia alkaloids is contraindicated in patients with active peptic ulcer or ulcerative colitis. Since rauwolfia alkaloids increase gastrointestinal motility and secretion, these conditions may be aggravated. Therapy with rauwolfia alkaloids should be administered cautiously in patients with a history of peptic ulcer or ulcerative colitis because of the risk of reactivation.

References:
  • "Product Information. Hydropres (reserpine-hydrochlorothiazide)." Merck & Co, Inc, West Point, PA.
Reserpine, hydralazine, and hydrochlorothiazide

Generic Name: hydralazine / hydrochlorothiazide / reserpine

Brand Name:

Synonyms: Reserpine, hydralazine, and hydrochlorothiazide (Oral)