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Reglan (Metoclopramide Injection Solution) and Pheochromocytoma

Result of checking the interaction of drug Reglan (Metoclopramide Injection Solution) and disease Pheochromocytoma for safety when used together.

Check result:

Reglan (Metoclopramide Injection Solution) <> Pheochromocytoma

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of metoclopramide is contraindicated in patients with pheochromocytoma. In a study involving patients with essential hypertension, intravenously administered metoclopramide was shown to induce the release of catecholamines. Hypertensive crises may occur in patients with pheochromocytoma due to induction of catecholamine release from the tumor.

References:

Abe M, Orita Y, Nakashima Y, Nakamura M "Hypertensive crisis induced by metoclopramide in patient with pheochromocytoma." Angiology 35 (1984): 122-8
Agabiti-Rosei E, Aliccandri CL, Corea L "Hyperstensive crisis in patients with phaeochromocytoma given metoclopramide." Lancet 1 (1977): 600
"Product Information. Reglan (metoclopramide)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Plouin PF, Menard J, Corval P "Hypertensive crisis in patient with phaeochromocytoma given metoclopramide." Lancet 2 (1976): 1357-8
Filibeck DJ, Grimm D, Forman WB, Leidner BA "Metoclopramide-induced hypertensive crisis." Clin Pharm 3 (1984): 548-9

Reglan (Metoclopramide Injection Solution)

Generic Name: metoclopramide

Brand Name: Reglan, Metozolv ODT

Synonyms: Reglan

What is Reglan (Metoclopramide Injection Solution)?