Drug search by name

Reglan (Metoclopramide Injection Solution) and Depression

Result of checking the interaction of drug Reglan (Metoclopramide Injection Solution) and disease Depression for safety when used together.

Check result:

Reglan (Metoclopramide Injection Solution) <> Depression

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Metoclopramide has been reported to cause mental depression in patients with and without a prior history of depression. Symptoms have ranged from mild to severe and have included suicidal ideation and suicide. Therapy with metoclopramide in patients with a history of mental depression, especially suicidal tendencies, should be administered cautiously, and only if benefits are anticipated to outweigh the potential risks. Some patients who experience depression with metoclopramide have improved following temporary discontinuation of the drug and reinstitution at a lower dosage with gradual titration.

References:

"Product Information. Reglan (metoclopramide)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Bottner RK, Tullio CJ "Metoclopramide and depression." Ann Intern Med 103 (1985): 482
Feder R "Metoclopramide and depression." J Clin Psychiatry 48 (1987): 38
Adams CD "Metoclopramide and depression." Ann Intern Med 103 (1985): 960
Weddington WW, Jr Banner A "Organic affective syndrome associated with metoclopramide: case report." J Clin Psychiatry 47 (1986): 208-9

Reglan (Metoclopramide Injection Solution)

Generic Name: metoclopramide

Brand Name: Reglan, Metozolv ODT

Synonyms: Reglan

What is Reglan (Metoclopramide Injection Solution)?