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Artemether and lumefantrine and QT prolongation

Result of checking the interaction of drug Artemether and lumefantrine and disease QT prolongation for safety when used together.

Check result:
Artemether and lumefantrine <> QT prolongation
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of certain antimalarial agents is contraindicated in patients with known prolongation of QT interval as they can develop fatal arrhythmias. It should also be avoided in patients with clinical conditions known to prolong the QT interval, such as a congenital prolongation of the QT interval or sudden death, uncorrected hypokalemia or hypomagnesemia, bradycardia, and certain cardiac conditions. Caution is advised in patients taking other medications that can prolong the QT interval.

References:
  • "Product Information. Quinine (quinine)." Zenith Goldline Pharmaceuticals, Fort Lauderdale, FL.
Artemether and lumefantrine

Generic Name: artemether / lumefantrine

Brand Name: Coartem

Synonyms: Artemether and Lumefantrine

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