About us Contacts Interactions: 118 620
Drug search by name

Ravicti and Hepatic impairment

Result of checking the interaction of drug Ravicti and disease Hepatic impairment for safety when used together.

Check result:
Ravicti <> Hepatic impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Patients with hepatic impairment may have higher plasma phenylacetate (PAA) and phenylacetate to phenylacetylglutamine (PAGN) ratio due to a reduced conversion capability of PAA to PAGN in the liver. Patients with moderate to severe hepatic impairment may require lower dosages of glycerol phenylbutyrate than normal to control the patient's ammonia levels. Caution is recommended in patients with hepatic impairment as no studies have been conducted.

Ravicti

Generic Name: glycerol phenylbutyrate

Brand Name: Ravicti

Synonyms: Ravicti Oral Liquid

Interaction with food and lifestyle
Drug interactions