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Prodrin and GERD
Result of checking the interaction of drug Prodrin and disease GERD for safety when used together.
Check result:
Prodrin <> GERD
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Methylxanthines increase gastric acidity and may also relax lower esophageal sphincter, which can lead to gastric reflux into the esophagus. Therapy with products containing methylxanthines should be administered cautiously in patients with significant gastroesophageal reflux.
References:
- American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association; (1994):
- Stoller JL "Oesophageal ulceration and theophylline." Lancet 2 (1985): 328-9
- "Product Information. Lufyllin (dyphylline)" Wallace Laboratories, Cranbury, NJ.
- Alterman P, Spiegel D, Feldman J, Yaretzky A "Histamine h2-receptor antagonists and chronic theophylline toxicity." Am Fam Physician 54 (1996): 1473
Prodrin
Generic Name: acetaminophen / caffeine / isometheptene mucate
Brand Name: Prodrin, MigraTen
Synonyms: n.a.
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