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Probenecid and Renal dysfunction

Result of checking the interaction of drug Probenecid and disease Renal dysfunction for safety when used together.

Check result:

Probenecid <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Probenecid may not be effective in patients with chronic renal insufficiency, particularly when glomerular filtration rate is 30 mL/min or less. Probenecid has been used in patients with some renal impairment but dosage requirements may be increased.

References:

Scott JT, O'Brien PK "Probenecid, nephrotic syndrome, and renal failure." Ann Rheum Dis 27 (1968): 249-52
"Product Information. Benemid (probenecid)." Merck & Co, Inc, West Point, PA.

Probenecid

Generic Name: probenecid

Brand Name: Benemid

Synonyms: n.a.

What is Probenecid?