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Prilocaine and Renal/hepatic dysfunction

Result of checking the interaction of drug Prilocaine and disease Renal/hepatic dysfunction for safety when used together.

Check result:

Prilocaine <> Renal/hepatic dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Prilocaine topical is absorbed through intact skin and mucosal membranes. Prolonged exposure, large doses, and/or application to compromised skin or mucosa can result in elevated plasma concentrations of prilocaine. Prilocaine is metabolized by the liver and to some extent by the kidney. The pharmacokinetic disposition of prilocaine is altered by changes in hepatic and renal function. Therapy with prilocaine topical should be administered cautiously and dosing modified for patients with compromised hepatic and renal function.

Prilocaine

Generic Name: prilocaine

Brand Name: Citanest Plain Dental

Synonyms: n.a.

What is Prilocaine?