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Potassium Chloride in Sodium Chloride and Acidosis

Result of checking the interaction of drug Potassium Chloride in Sodium Chloride and disease Acidosis for safety when used together.

Check result:

Potassium Chloride in Sodium Chloride <> Acidosis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Hypokalemia in patients with metabolic acidosis should be treated with an alkalinizing potassium salt (i.e. acetate, bicarbonate, citrate, or gluconate) rather than potassium chloride, since alkali therapy helps to promote cellular uptake of potassium. Close monitoring of acid-base balance, serum electrolytes, electrocardiogram, and clinical status is recommended.

References:

Leiter LA, Josse RG, West ML, Halperin ML "Severe metabolic acidosis induced in a patient during fasting by KCl administration." Clin Invest Med 11 (1988): 266-70
"Product Information. K-Dur (potassium chloride)." Schering Laboratories, Kenilworth, NJ.
Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, eds. "Harrison's Principles of Internal Medicine. 14th ed." New York, NY: McGraw-Hill Health Professionals Division (1998):

Potassium Chloride in Sodium Chloride

Generic Name: potassium chloride / sodium chloride

Brand Name: Buffered Salt, Thermotabs

Synonyms: Potassium chloride and sodium chloride

What is Potassium Chloride in Sodium Chloride?

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Potassium Chloride in Sodium Chloride <> Acidosis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

Consumer:

Administration of excessive amounts of sodium chloride can increase chloride concentrations and cause a loss of bicarbonate that results in metabolic acidosis. Clinical monitoring of acid/base balance and electrolyte concentrations is recommended.

References: