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Posaconazole oral/injection and Renal dysfunction

Result of checking the interaction of drug Posaconazole oral/injection and disease Renal dysfunction for safety when used together.

Check result:

Posaconazole oral/injection <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Posaconazole injection should be avoided in patients with moderate to severe renal impairment (GRF <50 mL/min), unless an assessment of the risks and benefits justifies its use. If used, serum creatinine levels should be closely monitored. No dose adjustment is needed in patients with mild or moderate renal dysfunction using oral suspension. Patients with severe renal dysfunction should be closely monitored for breakthrough fungal infections due to a variability in exposure. Similar recommendations apply for posaconazole delayed-release tablets although specific studies have not been conducted.

Posaconazole oral/injection

Generic Name: posaconazole

Brand Name: Noxafil

Synonyms: Posaconazole (oral/injection), Posaconazole

What is Posaconazole oral/injection?