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Poly Hist DM and BPH

Result of checking the interaction of drug Poly Hist DM and disease BPH for safety when used together.

Check result:
Poly Hist DM <> BPH
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sympathomimetic agents may cause or worsen urinary difficulty in patients with prostate enlargement due to smooth muscle contraction in the bladder neck via stimulation of alpha-1 adrenergic receptors. Therapy with sympathomimetic agents should be administered cautiously in patients with hypertrophy or neoplasm of the prostate.

References:
  • Williams DM "Phenylpropanolamine hydrochloride" Am Pharm NS30 (1990): 47-50
  • "Product Information. Sudafed (pseudoephedrine)." Glaxo Wellcome, Research Triangle Park, NC.
  • Covington TR, Lawson LC, Young LL, eds. "Handbook of Nonprescription Drugs. 10th ed." Washington, DC: American Pharmaceutical Association (1993):
Poly Hist DM

Generic Name: dextromethorphan / phenylephrine / pyrilamine

Brand Name: Codal-DM Syrup, Codimal DM, Codituss DM, Poly Hist DM, Viravan-DM, V-Tan DM, Zotex-12, Deconsal DM Tannate, Aldex DM, Viratan-DM, Triplex DM, MyHist-DM, Tannate V DM, Reme Hist DM, Pryil DM, Pyril DM

Synonyms: Dextromethorphan, phenylephrine, and pyrilamine, Pyril Mal Phenyl HCl Dex HBr

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