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Polycitra and Dehydration

Result of checking the interaction of drug Polycitra and disease Dehydration for safety when used together.

Check result:
Polycitra <> Dehydration
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Administration of potassium salts in severe dehydration may predispose to renal impairment. Therapy with potassium salts should be administered cautiously in patients with acute dehydration (e.g., due to severe or prolonged diarrhea or heat stress). Close monitoring of serum potassium concentrations is recommended, as potentially fatal hyperkalemia can develop rapidly and is often asymptomatic, manifested only by an increased potassium level (6.5 to 8 mEq/L) and characteristic electrocardiographic changes (peaking of T waves, loss of P waves, depression of ST segment, prolongation of the QT interval). Late manifestations include muscle paralysis and cardiovascular collapse from cardiac arrest (9 to 12 mEq/L). Continuous or serial electrocardiography may be appropriate in some patients during replacement therapy, particularly if given intravenously.

References:
  • "Product Information. Potassium Acetate (potassium acetate)." Abbott Pharmaceutical, Abbott Park, IL.
  • "Product Information. Kaon (potassium gluconate)." Savage Laboratories, Melville, NY.
  • "Product Information. K-Dur (potassium chloride)." Schering Laboratories, Kenilworth, NJ.
  • "Product Information. K-Lyte (potassium bicarbonate-potassium citrate)." Bristol-Myers Squibb, Princeton, NJ.
Polycitra

Generic Name: citric acid / potassium citrate / sodium citrate

Brand Name: Cytra-3, Polycitra, Polycitra-LC, Tricitrates, Virtrate-3

Synonyms: n.a.

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