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Pms-Haloperidol and Dehydration

Result of checking the interaction of drug Pms-Haloperidol and disease Dehydration for safety when used together.

Check result:
Pms-Haloperidol <> Dehydration
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Neuroleptic agents may cause hypotension (including orthostatic hypotension) and associated reflex tachycardia, syncope or dizziness, particularly during initiation of therapy or rapid escalation of dosage. Tolerance to the hypotensive effects often develops after a few doses to a few months. Rarely, fatal cardiac arrest has occurred secondary to severe hypotension. Therapy with neuroleptic agents should be administered cautiously in patients with conditions that would predispose them to hypotension, such as hypovolemia or dehydration (e.g., due to severe diarrhea or vomiting). In addition, neuroleptic agents can interfere with the body's ability to regulate core body temperature, occasionally producing hyperthermia during strenuous exercise, exposure to hot weather, and concomitant treatment with anticholinergic medications. Patients who are dehydrated may be particularly susceptible.

References:
  • "Product Information. Seroquel (quetiapine)." Zeneca Pharmaceuticals, Wilmington, DE.
  • "Product Information. Zyprexa (olanzapine)." Lilly, Eli and Company, Indianapolis, IN.
  • "Product Information. Geodon (ziprasidone)." Pfizer US Pharmaceuticals, New York, NY.
Pms-Haloperidol

Generic Name: haloperidol

Brand Name: Haldol, Haldol Decanoate

Synonyms: Haloperidol

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