Drug search by name

Placidyl and Renal/liver disease

Result of checking the interaction of drug Placidyl and disease Renal/liver disease for safety when used together.

Check result:

Placidyl <> Renal/liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Ethchlorvynol is thought to be metabolized by the liver and subsequently excreted in the urine, primarily as metabolites. Patients with renal and/or liver disease may be at greater risk for adverse effects from ethchlorvynol, including central nervous system and respiratory depression, due to decreased drug clearance. Therapy with ethchlorvynol should be administered cautiously in patients with impaired renal and/or hepatic function. In one study, patients with renal impairment experienced excessive drowsiness following repeated dosing of the drug, presumably due to its accumulation in the plasma.

References:

Dawborn JK, Turner A, Pattison G "Ethchlorvynol as a sedative in patients with renal failure." Med J Aust Sept (1972): 702-4
"Product Information. Placidyl (ethchlorvynol)." Abbott Pharmaceutical, Abbott Park, IL.

Placidyl

Generic Name: ethchlorvynol

Brand Name:

Synonyms: Placidyl (Oral)

What is Placidyl?