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Pitressin and Vascular disease

Result of checking the interaction of drug Pitressin and disease Vascular disease for safety when used together.

Check result:
Pitressin <> Vascular disease
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Vasopressin should not be used in patients with vascular disease, especially disease of the coronary arteries, except with extreme caution. In such patients, even small doses may precipitate anginal pain, and large doses may cause myocardial infarction. If a decision is made to use the drug, ECG monitoring should be performed periodically during therapy.

References:
  • Khokhar AM, Slater JD, Ma J, Ramage CM "The cardiovascular effect of vasopressin in relation to its plasma concentration in man and its relevance to high blood pressure." Clin Endocrinol (Oxf) 13 (1980): 259-66
  • Beller BM, Trevino A, Urban E "Pitressin-induced myocardial injury and depression in a young woman." Am J Med 51 (1971): 675-9
  • Brearley S, Hawker PC, Dykes PW, Keighley MR "A lethal complication of peripheral vein vasopressin infusion." Hepatogastroenterology 32 (1985): 224-5
  • Kelly KJ, Stang JM, Mekhjian HS "Vasopressin provocation of ventricular dysrhythmia." Ann Intern Med 92 (1980): 205-6
  • "Product Information. Pitressin (vasopressin)." Parke-Davis, Morris Plains, NJ.
  • Jacoby AG, Wiegman MV "Cardiovascular complications of intravenous vasopressin therapy." Focus Crit Care 17 (1990): 63-6
  • Colombani P "Upper extremity gangrene secondary to superior mesenteric artery infusion of vasopressin." Dig Dis Sci 27 (1982): 367-9
  • Greenwald RA, Rheingold OJ, Chiprut RO, Rogers AI "Local gangrene: a complication of peripheral Pitressin therapy for bleeding esophageal varices." Gastroenterology 74 (1978): 744-6
  • Wormser GP, Kornblee LV, Gottfried EB "Cutaneous necrosis following peripheral intravenous vasopressin therapy." Cutis 29 (1982): 249-52
  • Lambert M, de Peyer R, Muller AF "Reversible ischemic colitis after intravenous vasopressin therapy." JAMA 247 (1982): 666-7
  • Butow KW, de Witt TW, Jacobs FJ "Ornithine-vasopressin gangrene and reconstruction of the upper lip. Case report." J Craniomaxillofac Surg 17 (1989): 88-91
Pitressin

Generic Name: vasopressin

Brand Name: Pitressin Synthetic, Vasostrict, Pitressin

Synonyms: Pitressin Synthetic, Pitressin Injection

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