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Pitolisant Hydrochloride and Renal disease

Result of checking the interaction of drug Pitolisant Hydrochloride and disease Renal disease for safety when used together.

Check result:

Pitolisant Hydrochloride <> Renal disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The pharmacokinetics of pitolisant in patients with end-stage renal disease (ESRD) (eGFR of <15 mL/minute/1.73 m2) is unknown. Pitolisant is not recommended in patients with ESRD. It is recommended to adjust the dosage of pitolisant when using this agent in patients with moderate (eGFR 30 to 59 mL/minute/1.73 m2) and severe (eGFR 15 to 29 mL/minute/1.73 m2) renal impairment.

Pitolisant Hydrochloride

Generic Name: pitolisant

Brand Name: Wakix

Synonyms: Pitolisant

What is Pitolisant Hydrochloride?