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Pitolisant Hydrochloride and Hepatic impairment

Result of checking the interaction of drug Pitolisant Hydrochloride and disease Hepatic impairment for safety when used together.

Check result:

Pitolisant Hydrochloride <> Hepatic impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Pitolisant is contraindicated in patients with severe hepatic impairment. Pitolisant is extensively metabolized by the liver. Care should be exercised when using pitolisant in patients with moderate hepatic impairment. It is recommended to monitor patients with mild and moderate hepatic impairment and to adjust the dosage of pitolisant in patients with moderate hepatic impairment as appropriate. No dosage adjustment is recommended in patients with mild hepatic impairment.

Pitolisant Hydrochloride

Generic Name: pitolisant

Brand Name: Wakix

Synonyms: Pitolisant

What is Pitolisant Hydrochloride?