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Phenytoin injection and Thyroid function tests

Result of checking the interaction of drug Phenytoin injection and disease Thyroid function tests for safety when used together.

Check result:

Phenytoin injection <> Thyroid function tests

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Phenytoin may decrease serum PBI (protein-bound iodine) levels without associated thyroid disturbance. Free thyroxine concentrations may also be decreased, while resin or red cell T3 uptake values may be increased. Clinicians should be cognizant of these effects when prescribing or administering phenytoin therapy to patients with thyroid disorders.

References:

"Product Information. Dilantin (phenytoin)." Parke-Davis, Morris Plains, NJ.
Isojarvi JI, Pakarinen AJ, Myllyla VV "Thyroid function with antiepileptic drugs." Epilepsia 33 (1992): 142-8
"Product Information. Cerebyx (fosphenytoin)." Parke-Davis, Morris Plains, NJ.

Phenytoin injection

Generic Name: phenytoin

Brand Name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt

Synonyms: Phenytoin

What is Phenytoin injection?