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Pediazole and Myasthenia gravis

Result of checking the interaction of drug Pediazole and disease Myasthenia gravis for safety when used together.

Check result:

Pediazole <> Myasthenia gravis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis and trigger new onset of symptoms of myasthenic syndrome. Limited data suggest presynaptic suppression of acetylcholine release. Therapy with these agents should be administered cautiously in patients with a history of myasthenia gravis.

References:

May EF, Calvert PC "Aggravation of myasthenia gravis by erythromycin." Ann Neurol 28 (1990): 577-9
"Product Information. Ery-tab (erythromycin)." Abbott Pharmaceutical, Abbott Park, IL.

Pediazole

Generic Name: erythromycin / sulfisoxazole

Brand Name:

Synonyms: Pediazole (Oral)

What is Pediazole?