Drug search by name

Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid and Cardiovascular

Result of checking the interaction of drug Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid and disease Cardiovascular for safety when used together.

Check result:

Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid <> Cardiovascular

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Antihistamines may infrequently cause cardiovascular adverse effects related to their anticholinergic and local anesthetic (quinidine-like) activities. Tachycardia, palpitation, ECG changes, arrhythmias, hypotension, and hypertension have been reported. Although these effects are uncommon and usually limited to overdosage situations, the manufacturers and some clinicians recommend that therapy with antihistamines be administered cautiously in patients with cardiovascular disease, hypertension, and/or hyperthyroidism.

References:

"Product Information. Dimetane (brompheniramine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
"Product Information. Chlortrimeton (chlorpheniramine)." Schering-Plough, Liberty Corner, NJ.
"Product Information. Optimine (azatadine)." Schering Laboratories, Kenilworth, NJ.
"Product Information. Antivert (meclizine)." Roerig Division, New York, NY.
"Product Information. Tavist (clemastine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
"Product Information. Periactin (cyproheptadine)." Merck & Co, Inc, West Point, PA.
Smith SJ "Cardiovascular toxicity of antihistamines." Otolaryngol Head Neck Surg 111 Suppl (1994): 348-54
"Product Information. Zyrtec (cetirizine)." Pfizer US Pharmaceuticals, New York, NY.
"Product Information. Drixoral (dextromethorphan)." Schering-Plough, Liberty Corner, NJ.
Schuller DE, Turkewitz D "Adverse effects of antihistamines." Postgrad Med 79 (1986): 75-86
Woosley RL "Cardiac actions of antihistamines." Annu Rev Pharmacol Toxicol 36 (1996): 233-52
"Product Information. Benadryl (diphenhydramine)." Parke-Davis, Morris Plains, NJ.
"Product Information. Dramamine (dimenhydrinate)" Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO.
"Product Information. Vistaril (hydroxyzine)." Pfizer US Pharmaceuticals, New York, NY.

Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid

Generic Name: acetaminophen / dextromethorphan / doxylamine / pseudoephedrine

Brand Name: NyQuil D, Nyquil Hot Therapy, All-Nite Cold, Nyquil Cold Medicine, Nyquil Liquicap, Robitussin Night Cold, Tylenol Flu Night Time, Alka-Seltzer Plus Night Time Cold Liquigel, Tylenol Severe Cold & Flu Night Time, Night Time, Theraflu Nighttime Severe Cold, All-Nite Multi-Symptom Cold/Flu Relief, Multi-Symptom Nighttime, NyCair

Synonyms: Acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine

What is Acetaminophen, Dextromethorphan, Doxylamine, and Pseudoephedrine Liquid?