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Pacerone and Sinus node dysfunction

Result of checking the interaction of drug Pacerone and disease Sinus node dysfunction for safety when used together.

Check result:
Pacerone <> Sinus node dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of amiodarone is contraindicated for use in patients with cardiogenic shock, severe sinus node dysfunction causing marked sinus bradycardia, second- or third-degree AV block, or symptomatic bradycardia in the absence of a functioning pacemaker.

References:
  • Williamson BD, Hummel J, Niebauer M, Man C, Strickberger SA, Daoud E, Morady F "Bradycardia-facilitated polymorphic ventricular tachycardia caused by amiodarone after radiofrequency modification of atrioventricular conduction." Am Heart J 130 (1995): 399-401
  • Veltri EP, Reid PR "Sinus arrest with intravenous amiodarone." Am J Cardiol 58 (1986): 1110-1
  • "Product Information. Cordarone (amiodarone)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  • "Product Information. Cordarone Intravenous (amiodarone)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Pacerone

Generic Name: amiodarone

Brand Name: Pacerone, Cordarone, Nexterone

Synonyms: n.a.

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