About us Contacts Interactions: 118 620
Drug search by name

Orlistat and (fat soluble) vitamin deficiency

Result of checking the interaction of drug Orlistat and disease (fat soluble) vitamin deficiency for safety when used together.

Check result:
Orlistat <> (fat soluble) vitamin deficiency
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

At the recommended therapeutic dosage of 120 mg three times a day, orlistat inhibits dietary fat absorption by approximately 30% and has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene. Therapy with orlistat should be administered cautiously in patients with preexisting deficiency of one or more fat-soluble vitamins (A, D, E and K). Ideally, the deficiency should be corrected prior to initiation of therapy. A multivitamin supplement containing fat-soluble vitamins is recommended during therapy, best taken once a day at least 2 hours before or after the administration of orlistat.

References:
  • "Product Information. Xenical (orlistat)." Roche Laboratories, Nutley, NJ.
Orlistat

Generic Name: orlistat

Brand Name: Alli, Xenical, Alli

Synonyms: n.a.

Interaction with food and lifestyle
Drug interactions