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Omeprazole, Clarithromycin, and Amoxicillin and Myasthenia gravis

Result of checking the interaction of drug Omeprazole, Clarithromycin, and Amoxicillin and disease Myasthenia gravis for safety when used together.

Check result:

Omeprazole, Clarithromycin, and Amoxicillin <> Myasthenia gravis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis and trigger new onset of symptoms of myasthenic syndrome. Limited data suggest presynaptic suppression of acetylcholine release. Therapy with these agents should be administered cautiously in patients with a history of myasthenia gravis.

References:

May EF, Calvert PC "Aggravation of myasthenia gravis by erythromycin." Ann Neurol 28 (1990): 577-9
"Product Information. Ery-tab (erythromycin)." Abbott Pharmaceutical, Abbott Park, IL.

Omeprazole, Clarithromycin, and Amoxicillin

Generic Name: amoxicillin / clarithromycin / omeprazole

Brand Name: Omeclamox-Pak

Synonyms: Amoxicillin, clarithromycin, and omeprazole

What is Omeprazole, Clarithromycin, and Amoxicillin?