Olumiant and Renal dysfunction
Result of checking the interaction of drug Olumiant and disease Renal dysfunction for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Renal elimination is the principal clearance mechanism for baricitinib through filtration and active secretion. Baricitinib is not recommended in patients with moderate or severe renal impairment (estimated GFR of less than 60 mL/min/1.73 m2). Renal function was found to significantly affect baricitinib exposure. Care should be exercise when using this agent in patients with renal dysfunction.