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Novaplus HydrALAZINE Hydrochloride and Coronary artery disease
Result of checking the interaction of drug Novaplus HydrALAZINE Hydrochloride and disease Coronary artery disease for safety when used together.
Check result:
Novaplus HydrALAZINE Hydrochloride <> Coronary artery disease
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:The use of hydralazine is contraindicated in patients with coronary artery disease. Reflex tachycardia may commonly occur. Palpitations and chest pain have also been reported. Myocardial infarction has been associated with the use of hydralazine.
References:
- Packer M, Meller J, Medina N, et al "Provocation of myocardial ischemic events during initiation of vasodilator therapy for severe chronic heart failure." Am J Cardiol 48 (1981): 939-46
- Laslett LJ, DeMaria AN, Amsterdam EA, Mason DT "Hydralazine-induced tachycardia and sodium retention in heart failure: hemodynamic and symptomatic correlation by prazosin therapy." Arch Intern Med 138 (1978): 819-20
- Koch-Weser J "Hydralazine." N Engl J Med 295 (1976): 320-3
Novaplus HydrALAZINE Hydrochloride
Generic Name: hydralazine
Brand Name: Apresoline
Synonyms: Hydralazine, HydrALAZINE
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