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Nipent and Myelosuppression

Result of checking the interaction of drug Nipent and disease Myelosuppression for safety when used together.

Check result:

Nipent <> Myelosuppression

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Pentostatin can induce myelosuppression, primarily during the initial courses of therapy. Disease status, including a bone marrow examination, should be determined if severe neutropenia continues. Patients should be instructed to immediately report any signs or symptoms suggesting bone marrow suppression such as fever, sore throat, local infection, bleeding or symptoms of anemia. Therapy with pentostatin should be administered cautiously in patients with bone marrow suppression. Close clinical monitoring of hematopoietic function is necessary.

References:

Cheson BD "Infectious and immunosuppressive complications of purine analog therapy." J Clin Oncol 13 (1995): 2431-48
Kraut EH, Neff JC, Bouroncle BA, Gochnour D, Grever MR "Immunosuppressive effects of pentostatin." J Clin Oncol 8 (1990): 848-55
"Product Information. Nipent (pentostatin)." Hospira Inc, Lake Forest, IL.

Nipent

Generic Name: pentostatin

Brand Name: Nipent

Synonyms: n.a.

What is Nipent?