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Nilandron and Interstitial pneumonitis

Result of checking the interaction of drug Nilandron and disease Interstitial pneumonitis for safety when used together.

Check result:
Nilandron <> Interstitial pneumonitis
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of nilutamide is contraindicated in patients with severe respiratory impairment. Patients with pulmonary dysfunction may be at increased risk for nilutamide- associated interstitial pneumonitis. Patients should be instructed to immediately report any signs or symptoms of respiratory impairment such as dyspnea, cough, chest pain, or fever. Clinical monitoring of pulmonary function, including pre-treatment chest X-ray, is recommended.

References:
  • Gomez JL, Dupont A, Cusan L, Tremblay M, Tremblay M, Labrie F "Simultanwous liver and lung toxicity related to the nonsteroidal antiandrogen nilutamide (Anandron): a case report." Am J Med 92 (1992): 563-6
  • Gomez JL, Dupont A, Cusan L, Tremblay M, Tremblay M, Labrie F "Simultaneous liver and lung toxicity related to the nonsteroidal antiandrogen nilutamide (Anandron): a case report." Am J Med 92 (1992): 563-6
  • Wieder JA, Soloway MS "Interstitial pneumonitis associated with neoadjuvant leuprolide and nilutamide for prostate cancer." J Urol 159 (1998): 2099
  • "Product Information. Nilandron (nilutamide)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Nilandron

Generic Name: nilutamide

Brand Name: Nilandron

Synonyms: n.a.

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