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Nicotine Oral, Transdermal and CVD/PVD

Result of checking the interaction of drug Nicotine Oral, Transdermal and disease CVD/PVD for safety when used together.

Check result:

Nicotine Oral, Transdermal <> CVD/PVD

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Nicotine has dose-dependent cardiovascular effects. At dosages used for smoking cessation, nicotine may produce peripheral vasoconstriction and increase heart rate, myocardial contractility and blood pressure. Although these effects are relatively minor and clinically insignificant in most healthy individuals, complications may occasionally occur in patients with underlying cardiovascular disease, particularly if they continue to smoke during nicotine therapy. Therapy with nicotine should be administered cautiously in patients with coronary artery disease, cardiac arrhythmias, and peripheral vascular disease. In general, nicotine therapy should be avoided during the immediate postmyocardial infarction period, in severe or worsening angina, and in life-threatening arrhythmias. All patients should stop smoking completely during nicotine replacement therapy.

References:

Rennard S, Daughton D, Cheney R, Thompson A, Miles R, Windle J, Repsher L, Clifford DP, Schones W, Fortmann SP, Killen JD, Pe "Nicotine replacement therapy for patients with coronary artery disease." Arch Intern Med 154 (1994): 989-95
Warner JG, Little WC "Myocardial infarction in a patient who smoked while wearing a nicotine patch." Ann Intern Med 120 (1994): 695
Khosla S, Laddu A, Ehrenpreis S, Somberg JC "Cardiovascular effects of nicotine: relation to deleterious effects of cigarette smoking." Am Heart J 127 (1994): 1669-72
"Product Information. Nicorette (nicotine)." SmithKline Beecham, Philadelphia, PA.
"Product Information. Habitrol (nicotine)." Basel Pharmaceuticals, Summit, NJ.

Nicotine Oral, Transdermal

Generic Name: nicotine

Brand Name: Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Commit, Habitrol, Nicoderm C-Q, Nicotine System Kit, Nicoderm CQ, Nicotrol Inhaler, Nicotrol NS

Synonyms: Nicotine Gum and Lozenges, Nicotine

What is Nicotine Oral, Transdermal?