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Nevirapine Tablets and Renal dysfunction

Result of checking the interaction of drug Nevirapine Tablets and disease Renal dysfunction for safety when used together.

Check result:

Nevirapine Tablets <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Nevirapine metabolites are primarily eliminated by the kidney. The clinical significance of possible reduced metabolite clearance in renal impairment is uncertain. Therapy with nevirapine should be administered cautiously in patients with renal impairment.

References:

Havlir D, Cheeseman SH, McLaughlin M, Murphy R, Erice A, Spector SA, Greenough TC, Sullivan JL, Hall D, Myers M, et al "High-dose nevirapine: safety, pharmacokinetics, and antiviral effect in patients with human immunodeficiency virus infection." J Infect Dis 171 (1995): 537-45
Cheeseman SH, Hattox SE, McLaughlin MM, Koup RA, Andrews C, Bova CA, Pav JW, Roy T, Sullivan JL, Keirns JJ "Pharmacokinetics of nevirapine: initial single-rising-dose study in humans." Antimicrob Agents Chemother 37 (1993): 178-82
"Product Information. Viramune (nevirapine)." Boehringer-Ingelheim, Ridgefield, CT.

Nevirapine Tablets

Generic Name: nevirapine

Brand Name: Viramune, Viramune XR

Synonyms: Nevirapine

What is Nevirapine Tablets?