Netupitant and palonosetron and Severe hepatic impairment
Result of checking the interaction of drug Netupitant and palonosetron and disease Severe hepatic impairment for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Limited data are available with fosnetupitant (only available in combination with palonosetron in the US) in patients with severe hepatic impairment (Child-Pugh score greater than 9), therefore, its use should be avoided in these patients. No dosage adjustment is necessary for patients with mild to moderate hepatic impairment (Child-Pugh score 5 to 8).
Generic Name: netupitant / palonosetron
Brand Name: Akynzeo
Synonyms: Netupitant and Palonosetron
Netupitant and palonosetron - ciężkie zaburzenia czynności wątroby 
Netupitant and palonosetron - insuficiência hepática grave 
Netupitant and palonosetron - gangguan hati yang teruk 
Netupitant and palonosetron - kerusakan hati yang parah 
Netupitant and palonosetron - grave insufficienza epatica 
Netupitant and palonosetron - insuffisance hépatique sévère 
Netupitant and palonosetron - schwere Leberfunktionsstörung 
Netupitant and palonosetron - insuficiencia hepática grave 
Netupitant and palonosetron - тяжелая печеночная недостаточность 
Netupitant and palonosetron - şiddetli karaciğer yetmezliği 
Netupitant and palonosetron - القصور الكبدي الشديد 
Netupitant and palonosetron - 严重肝功能不全