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Nelfinavir and Liver disease

Result of checking the interaction of drug Nelfinavir and disease Liver disease for safety when used together.

Check result:

Nelfinavir <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Nelfinavir is primarily metabolized by the liver. Patients with liver disease may be at greater risk for adverse effects from nelfinavir due to decreased drug clearance. Therapy with nelfinavir should be administered cautiously in patients with liver disease.

References:

Sommadossi JP "HIV protease inhibitors: pharmacologic and metabolic distinctions." AIDS 13 (1999): s29-40
"Product Information. Viracept (nelfinavir)." Agouron Pharma Inc, La Jolla, CA.

Nelfinavir

Generic Name: nelfinavir

Brand Name: Viracept

Synonyms: n.a.

What is Nelfinavir?