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Nalbuphine Injection and Intracranial pressure

Result of checking the interaction of drug Nalbuphine Injection and disease Intracranial pressure for safety when used together.

Check result:

Nalbuphine Injection <> Intracranial pressure

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The hypoventilation associated with administration of opiate partial agonists can induce cerebral hypoxia and vasodilatation with resultant increase in intracranial pressure. Unless mechanical ventilation is provided, extreme caution is advised when opiate partial agonists are given to patients head injury, intracranial lesions, or a preexisting elevated CSF pressure. Also, clinicians treating such patients should be aware that opiate partial agonists may interfere with the evaluation of CNS function, especially with respect to consciousness levels, respiratory status, and pupillary changes.

References:

"Product Information. Dalgan (dezocine)." Astra USA, Westborough, MA.
"Product Information. Stadol (butorphanol)." Allscrips Pharmaceutical Company, Vernon Hills, IL.
"Product Information. Talwin NX (pentazocine)." Sanofi Winthrop Pharmaceuticals, New York, NY.
"Product Information. Buprenex (buprenorphine)." Reckitt and Colman Pharmaceutical, Richmond, VA.
"Product Information. Stadol (butorphanol nasal)." Bristol-Myers Squibb, Princeton, NJ.
"Product Information. Nubain (nalbuphine)." Endo Laboratories, Texarkana, TX.

Nalbuphine Injection

Generic Name: nalbuphine

Brand Name: Nubain

Synonyms: Nalbuphine

What is Nalbuphine Injection?