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Mycobutin and Neutropenia/thrombocytopenia
Result of checking the interaction of drug Mycobutin and disease Neutropenia/thrombocytopenia for safety when used together.
Check result:
Mycobutin <> Neutropenia/thrombocytopenia
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Rifabutin may occasionally cause neutropenia and rarely, thrombocytopenia. Patients with preexisting neutropenia and/or thrombocytopenia should be monitored closely during rifabutin therapy for further decreases in blood counts, and therapy discontinued if appropriate.
References:
- "Product Information. Mycobutin (rifabutin)." Pharmacia and Upjohn, Kalamazoo, MI.
- Siegal FP, Eilbott D, Burger H, et al "Dose-limiting toxicity of rifabutin in AIDS-related complex: syndrome of arthralgia/arthritis." AIDS 4 (1990): 433-41
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