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Moxifloxacin (Systemic) and Liver disease

Generic Name: moxifloxacin
Dosage Forms: n.a.
Other Brand Names: Avelox , Avelox IV

Result of checking the interaction of drug Moxifloxacin (Systemic) and disease Liver disease for safety when used together.

Check result:

Moxifloxacin (Systemic) <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Moxifloxacin is primarily metabolized by the liver via glucuronide and sulfate conjugation and may accumulate in patients with impaired hepatic function. Therapy with moxifloxacin should be administered cautiously in patients with liver disease. Dosage adjustments are not necessary in patients with mild hepatic insufficiency (Child Pugh Class A). Due to a lack of clinical data, use is not recommended in patients with moderate or severe hepatic insufficiency.

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