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Mitotane and Liver dysfunction
Result of checking the interaction of drug Mitotane and disease Liver dysfunction for safety when used together.
Check result:
Mitotane <> Liver dysfunction
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Mitotane is primarily metabolized by the liver. Metabolism and therapeutic activity may be altered in patients with hepatic impairment. Therapy with mitotane should be administered cautiously in patients with hepatic impairment. Clinical monitoring of hepatic function is recommended.
References:
- "Product Information. Lysodren (mitotane)." Bristol-Myers Squibb, Princeton, NJ.
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