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Mitomycin Intravenous and Renal dysfunction

Generic Name: mitomycin
Dosage Forms: n.a.
Other Brand Names: Mutamycin

Result of checking the interaction of drug Mitomycin Intravenous and disease Renal dysfunction for safety when used together.

Check result:

Mitomycin Intravenous <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Elevations in BUN and/or serum creatinine have been reported during mitomycin therapy. Therapy with mitomycin should not be administered to patients with serum creatinine > 1.7 mg/dl. Hemolytic Uremic Syndrome (HUS) has been reported during mitomycin therapy. The incidence of HUS appears to be increased in patients receiving total doses of mitomycin > 60 mg. Blood product transfusion may exacerbate the symptoms of HUS. Clinical monitoring of renal function is recommended.

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