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Mitomycin Intravenous and Bleeding disorders

Result of checking the interaction of drug Mitomycin Intravenous and disease Bleeding disorders for safety when used together.

Check result:
Mitomycin Intravenous <> Bleeding disorders
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of mitomycin is contraindicated in patients with thrombocytopenia, coagulation disorders, or an increase in bleeding tendency. Mitomycin induces cumulative, delayed myelosuppression. Neutropenia and thrombocytopenia can occur anytime within eight weeks after initiation of therapy. Therapy with mitomycin should be withheld if platelet counts fall below 100,000/mm3 and subsequent dosages modified based on the nadir of the previous dose.

References:
  • "Product Information. Mutamycin (mitomycin)." Bristol-Myers Squibb, Princeton, NJ.
Mitomycin Intravenous

Generic Name: mitomycin

Brand Name: Mutamycin

Synonyms: Mitomycin, MitoMYcin (Systemic)

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