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Mirtazapine Orally Disintegrating Tablets and Seizures

Result of checking the interaction of drug Mirtazapine Orally Disintegrating Tablets and disease Seizures for safety when used together.

Check result:
Mirtazapine Orally Disintegrating Tablets <> Seizures
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of tricyclic and tetracyclic antidepressants is associated with a risk of seizures. Only one case of seizure was reported with mirtazapine, a newer tetracyclic antidepressant, during premarketing trials involving nearly 2800 patients. However, the drug has not been evaluated in controlled studies of patients with a history of seizures. Therapy with mirtazapine should be administered cautiously in such patients.

References:
  • Hoyberg OJ, Maragakis B, Mullin J, Norum D, Stordall E, Ekdahl P, Ose E, Moksnes KM, Sennef C "A double-blind multicentre comparison of mirtazapine and amitriptyline in elderly depressed patients." Acta Psychiatr Scand 93 (1996): 184-90
  • "Product Information. Remeron (mirtazapine)." Organon, West Orange, NJ.
  • Smith WT, Glaudin V, Panagides J, Gilvary E "Mirtazapine vs. amitriptyline vs. placebo in the treatment of major depressive disorder." Psychopharmacol Bull 26 (1990): 191-6
Mirtazapine Orally Disintegrating Tablets

Generic Name: mirtazapine

Brand Name: Remeron, Remeron SolTab

Synonyms: Mirtazapine

Interaction with food and lifestyle