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Mirtazapine Orally Disintegrating Tablets and Renal/liver disease

Result of checking the interaction of drug Mirtazapine Orally Disintegrating Tablets and disease Renal/liver disease for safety when used together.

Check result:

Mirtazapine Orally Disintegrating Tablets <> Renal/liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Mirtazapine is extensively metabolized by the liver. Both the parent drug and metabolites, some of which are pharmacologically active, are excreted by the kidney. The clearance of mirtazapine has been shown to decrease in patients with moderate to severe renal or hepatic impairment. Therapy with mirtazapine should be administered cautiously in such patients. Dosage adjustments may be necessary.

References:

Montgomery SA "Safety of mirtazapine: a review." Int Clin Psychopharmacol 10(suppl 4 (1995): 37-45
Davis R, Wilde MI "Mirtazapine: a review of its pharmacology and therapeutic potential in the management of major depression." Cns Drugs 5 (1996): 389-402
"Product Information. Remeron (mirtazapine)." Organon, West Orange, NJ.

Mirtazapine Orally Disintegrating Tablets

Generic Name: mirtazapine

Brand Name: Remeron, Remeron SolTab

Synonyms: Mirtazapine

What is Mirtazapine Orally Disintegrating Tablets?