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Mirapex ER and Renal function disorders

Result of checking the interaction of drug Mirapex ER and disease Renal function disorders for safety when used together.

Check result:

Mirapex ER <> Renal function disorders

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Pramipexole is eliminated by the kidneys, and approximately 90% of the drug is excreted unchanged in the urine. Renal insufficiency decreases the renal clearance and increases the half-life. Therapy with pramipexole should be administered cautiously and at a reduced dose in patients with compromised renal function. Pramipexole clearance is extremely low in dialysis patients, as a negligible amount of the drug is removed by it.

References:

"Product Information. Mirapex (pramipexole)." Boehringer Ingelheim, Ridgefield, CT.
Wright CE, Sisson TL, Ichhpurani AK, Peters GR "Steady-state pharmacokinetic properties of pramipexole in healthy volunteers." J Clin Pharmacol 37 (1997): 520-5

Mirapex ER

Generic Name: pramipexole

Brand Name: Mirapex, Mirapex ER

Synonyms: n.a.

What is Mirapex ER?