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Mintezol and Liver disease

Result of checking the interaction of drug Mintezol and disease Liver disease for safety when used together.

Check result:
Mintezol <> Liver disease
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Thiabendazole is extensively metabolized by the liver. Therapy with thiabendazole should be administered cautiously and with careful monitoring in patients with liver disease.

References:
  • Roy MA, Nugent FW, Aretz HT "Micronodular cirrhosis after thiabendazole." Dig Dis Sci 34 (1989): 938-41
  • Tocco DJ, Rosenblum C, Martin CM, Robinson HJ "Absorption, metabolism, and excretion of thiabendazole in man and laboratory animals." Toxicol Appl Pharmacol 9 (1966): 31-9
  • Bion E, Pariente EA, Maitre F "Severe cholestasis and sicca syndrome after thiabendazole." J Hepatol 23 (1995): 762-3
  • Fink AI, MacKay CJ, Cutler SS "Sicca complex and cholangiostatic jaundice in two members of a family probably caused by thiabendazole." Ophthalmology 86 (1979): 1892-6
  • "Product Information. Mintezol (thiabendazole)." Merck & Co, Inc, West Point, PA.
Mintezol

Generic Name: thiabendazole

Brand Name:

Synonyms: n.a.

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