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Minoxidil (Systemic) and Renal failure/dialysis

Result of checking the interaction of drug Minoxidil (Systemic) and disease Renal failure/dialysis for safety when used together.

Check result:

Minoxidil (Systemic) <> Renal failure/dialysis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Patients with renal failure or on dialysis may require a lower dosage of minoxidil as 21% of a dose is excreted unchanged in the urine. Close medical supervision is advised to prevent exacerbation of renal failure or precipitation of cardiac failure.

References:

"Product Information. Loniten (minoxidil)." Pharmacia and Upjohn, Kalamazoo, MI.
Lowenthal DT, Onesti G, Mutterperl R, Affrime M, Martinez EW, Kim KE, Busby P, Shirk J, Swartz C "Long-term clinical effects, bioavailability, and kinetics of minoxidil in relation to renal function." J Clin Pharmacol 18 (1978): 500-8
Halstenson CE, Opsahl JA, Wright CE, et al "Disposition of minoxidil in patients with various degrees of renal function." J Clin Pharmacol 29 (1989): 798-802

Minoxidil (Systemic)

Generic Name: minoxidil

Brand Name: Loniten

Synonyms: Minoxidil

What is Minoxidil (Systemic)?